The Centre of Research Excellence (CRE) to Reduce Inequality in Heart Disease focuses on improving the heart health and outcomes of groups and communities i.e. Regional Australians, Indigenous Australians and International Health

Mr. Jordan Loader

Following the successful completion of a Bachelor of Exercise Science (Honours) degree in 2009, Jordan shifted his research focus prior to beginning his PhD programme from elite athletic performance and Sports Sciences to translational, clinical, and basic research in the area of cardiovascular function and disease. Jordan began his current PhD programme as a part-time candidate in early 2014 under the supervision of Dr. Christian Lorenzen, the Deputy Head for the School of Exercise Science at the Australian Catholic University. In recognition of his advanced progress and unique achievements within his first 6-months of full time equivalent PhD candidature, Jordan was offered a Postgraduate Award from the Centre of Research Excellence in 2015 to continue his PhD research as a full time candidate under the co-supervision of Prof. Simon Stewart, the Director of the Mary MacKillop Institute for Health Research, and Dr. Christian Lorenzen.

 

Jordan's PhD research focuses on the short- and long-term effects of excess sugar consumption, with a special interest in commercial sugary drink ingestion on endothelial and vascular smooth muscle function in the micro- and macrocirculation of healthy subjects and those with cardiometabolic diseases. In addition to his main research foci, Jordan has developed expertise in the assessment of microvascular function using laser imaging with transdermal iontophoresis and has provided consultation to international researchers to improve the reproducibility and reliability of their protocols for assessing the microcirculation. While improving techniques for earlier detection of vascular dysfunction, Jordan's research will have immediate translational impact further informing global public health policies of the adverse effects of excess sugar consumption and its role in the pathogenesis of cardiometabolic and cardiovascular diseases. 

  

Jordan has demonstrated strong international collaboration throughout his PhD programme with Associate Prof Guillaume Walther of the University of Avignon, France, assuming the role of Associate Supervisor and aiding in research design. In addition to linking the Centre of Research Excellence to the University of Avignon, Jordan has collaborated with other international researchers from across Europe, as well as independently establishing an ongoing research connection with the Beth Israel Deaconess Medical Center (BIDMC) and Harvard Medical School. Jordan is currently performing research towards his Australian PhD programme as a visiting graduate student of Harvard Medical School at BIDMC in Boston, USA. Furthermore, Jordan has been appointed as a co-investigator in several BIDMC lead and NIH funded studies outside of his core PhD curriculum that focus on the interaction between microvascular dysfunction and neuropathy in the development of diabetic foot ulcers and the subsequent impaired healing rate, as well as a major clinical trials investigating the efficacy of a specific stem-cell therapy to improve diabetic neuropathy. In mid 2016, Jordan will finish his programme at Harvard University and will travel to France to begin a Research Fellowship at the University of Avignon in fulfilment of his 2016 Endeavour Research Fellowship.     

 

Jordan is a current PhD candidate who is performing research under a Centre of Research Excellence Postgraduate Award and Travel Scholarship to optimise outcomes in cardiovascular disease.

  1. Loader, J., Montero, D., Lorenzen, C., Watts, R., Méziat, C., Reboul, C., Stewart, S., Walther, G. (2015). Acute hyperglycemia impairs vascular function in healthy and cardiometabolic diseased subjects: systematic review and meta-analysis. Arteriosclerosis, Thrombosis, and Vascular Biology.
  2. Loader, J., Montgomery, P., Williams, M.D., Lorenzen, C., Kemp, J.G. (2012). Classifying training drills based on movement demands in Australian Football. International Journal of Sports Science & Coaching7, 1, 57-67.

Jordan has also receved the 2015 NHMRC Dora Lush Biomedical Research Postgraduate Scholarship and 2016 Endeavour Research Fellowship award.