The Centre of Research Excellence (CRE) to Reduce Inequality in Heart Disease focuses on improving the heart health and outcomes of groups and communities i.e. Regional Australians, Indigenous Australians and International Health

Professor Paul Scuffham

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Professor Paul Scuffham is an expert in health economics and has published over 250 articles in peer reviewed journals.  He is the Director of one of the largest health economics groups in Australasia - the Centre for Applied Health Economics in the School of Medicine at Griffith University, and is the Deputy Director of the Menzies Health Institute Queensland. He established the Australian Chapter of the International Society for Pharmacoeconomics and Outcomes Research (ISPOR).

 

Professor Scuffham’s research efforts have focused on: a) estimating the value for money from cardiac interventions across the disease continuum; b) measuring quality of life with multi-attribute utility instruments, and c) eliciting preferences for healthcare, including the measurement and valuation of health states, and d) methods of priority setting in healthcare.  Consistent with the focus of the CRE to Reduce Inequality in Heart Disease, he has applied these methods in a portfolio of health services research including whole population studies to multicentre, randomised controlled trials of multidisciplinary interventions, and in cohort studies of mothers and children.

 

Professor Scuffham is a Chief Investigator of the CRE to Reduce Inequality of Heart Disease. He works closely with the other Investigators to meet the CRE’s aims and objectives, support the early-to-mid career researchers being funded via the CRE and provide key scientific input to ensure the CRE’s planned portfolio of research is successfully undertaken.  

 

Chronic heart disease

  1. Scuffham PA, Ball J, Horowitz JD, Wong C, Newton PJ, Macdonald P, McVeigh J, Rischbieth A, Emanuele N, Carrington MJ, Reid CM, Chan YK, Stewart S,; WHICH? II Trial Investigators. Standard versus intensified management of heart failure to reduce healthcare costs: Results of a multicentre, randomised controlled trial. European Heart Journal 2017; 38:2340–2348 doi: 10.1093/eurheartj/ehx259. https://academic.oup.com/eurheartj/article-lookup/doi/10.1093/eurheartj/ehx259
  2. Maru S, Byrnes J, Chan YK, Carrington M, Stewart S, Scuffham PA. Long-term cost-effectiveness of home versus clinic-based management of chronic heart failure: The WHICH? study (Which Heart Failure Intervention Is Most Cost-Effective & Consumer Friendly in Reducing Hospital Care). Journal of Medical Economics 2017: 20(4);318-27
  3. Kularatna S, Byrnes J, Chan YK, Carrington M, Stewart S, Scuffham PA. Comparison of contemporaneous responses for EQ-5D-3L and Minnesota Living with Heart Failure; A case for disease specific multi attribute utility instrument in cardiovascular conditions. International Journal of Cardiology 2017: 227; 172-76
  4. Byrnes J, Carrington MJ, Chan Y-K, Pollocino C, Dubrowin N, Stewart S, Scuffham PA. Cost-effectiveness of a home based intervention for secondary prevention of readmission with chronic heart disease. PLoS One 2015; 10(12):1-13
  5. Maru S, Byrnes J, Carrington MJ, Chan YK, Thompson DR, Stewart S, Scuffham PA. Cost-effectiveness of Home versus Clinic-Based Management of Chronic Heart Failure: Extended follow-up of a pragmatic, multicentre randomized trial cohort - The WHICH? Study (Which Heart Failure Intervention Is Most Cost-Effective & Consumer Friendly in Reducing Hospital Care). International Journal of Cardiology 2015; 8(201):368-375
  6. Stewart S, Ball J, Horowitz JD, Marwick TH, Mahadevan G, Wong C, Abhayaratna WP, Chan YK, Esterman A, Thompson DR, Scuffham PA, Carrington MJ. Standard versus atrial fibrillation-specific management strategy (SAFETY) to reduce recurrent admission and prolong survival: pragmatic, multicentre, randomised controlled trial. The Lancet 2015; 385(9970):775-784
  7. Stewart S, Chan Y-K, Wong C, Jennings G, Scuffham P, Esterman A, Carrington M, on behalf of the NIL-CHF Investigators. Impact of a nurse-led home and clinic-based secondary prevention programme to prevent progressive cardiac dysfunction in high-risk individuals: the Nurse-led Intervention for Less Chronic Heart Failure (NIL-CHF) randomized controlled study. European Journal of Heart Failure 2015; 17(6):620-630
  8. Stewart S, Carrington MJ, Horowitz JD, Marwick TH, Newton PJ, Davidson PM, Macdonald PM, Thompson DR, Chan YK, Krum H, Reid C, Scuffham PA. Prolonged impact of home versus clinic-based management of chronic heart failure: extended follow-up of a pragmatic, multicentre randomized trial cohort. International Journal of Cardiology 2014; 174:600-610
  9. Stewart S, Carrington MJ, Chan YK, Goldstein S, Esterman A, Calderone A, Scuffham PA. A multicentre, randomized trial of a nurse-led, home-based intervention for optimal secondary cardiac prevention suggests some benefits for men but not for women: the Young @ Heart Study. Circulation: Cardiovascular Quality and Outcomes 2013; 6(4):379-389
  10. Stewart S, Carrington MJ, Goldstein S, Scuffham P. Differential impact of a nurse-led, home-based intervention for optimal secondary cardiac prevention on recurrent hospitalization in men and women: the Young @ Heart multicentre, randomized trial. European Heart Journal 2013; 34.
  11. Stewart SCarrington MJ, Marwick TH, Davidson PM, Macdonald P, Horowitz JD, Krum H, Newton PJ, Reid C, Chan YK, Scuffham PA. Impact of Home Versus Clinic-Based Management of Chronic Heart Failure: The WHICH? (Which Heart Failure Intervention Is Most Cost-Effective & Consumer Friendly in Reducing Hospital Care) Multicenter, Randomized Trial. J Am Coll Cardiol. 2012;60(14):1239-48.
  12. Carrington MJ, Ball J, Horowitz JD, Marwick TH, Mahadevan G, Wong C, Abhayaratna WP, Haluska B, Thompson DR, Scuffham PA, Stewart S. Navigating the fine line between benefit and risk in chronic atrial fibrillation: Rationale and design of the Standard versus Atrial Fibrillation spEcific managemenT studY (SAFETY). International Journal of Cardiology 2013; 166(2):359-365
  13. Carrington MJ, Ball J, Horowitz JD, Marwick TH, Mahadevan G, Wong C, Abhayaratna WP, Haluska B, Thompson DRScuffham PAStewart S. Navigating the fine line between benefit and risk in chronic atrial fibrillation: Rationale and design of the Standard versus Atrial Fibrillation spEcific managemenT studY (SAFETY). Int J Cardiol 2013; 166: 359-65.
  14. Chan YK, Stewart S, Calderone A, Scuffham PA, Goldstein S, Carrington MJ. Exploring the potential to remain "Young @ Heart": Initial findings of a multi-centre, randomised study of nurse-led, home-based intervention in a hybrid health care system. Int J Cardiol. 2012;154(1):52-8.
  15. Ingles J, Yeates L, O’Brien L, McGaughran J, Scuffham PA, Atherton J, Semsarian C.  Genetic Testing for Inherited Heart Diseases: Longitudinal impact on health-related quality of life.  Genetics in Medicine 2012;14:749-52
  16. Ingles J, McGaughran J, Scuffham PA, Atherton J, Semsarian C.  A Cost-Effectiveness Model of Genetic Testing for the Evaluation of Families with Hypertrophic Cardiomyopathy.  Heart 2012; 98(8), 625-630.
  17. Mudge AM, Denaro CP, Scott A, Javorsky G, Adsett JA, Mullins RW, Suna JM, Meyers D, O’Rourke P, Scuffham PA, Marwick TH.  Exercise Joins Education: Combined therapy to improve outcomes in newly-discharged heart failure patients (EJECTION-HF).  European Journal of Heart Failure  2011 Dec;13(12):1370-5.
  18. Hirst N, Whitty JA, Eely D, Scuffham PA.  Predictors of Government Subsidised Pharmaceutical use in Patients With Diabetes or Cardiovascular Disease in a Primary Care Setting: Evidence from a prospective randomised trial.  Journal of Medical Economics 2011; 14(6):698-70

 International heart health

  1. Marwick TH, Scuffham PA, Hunnick M. Selection for Early Surgery in Asymptomatic Mitral Regurgitation:       A Markov Model. International Journal of Cardiology 2013; 165(2):266-272
  2. Milne R, Lennon D, Stewart J, Vander Hoorn S, Scuffham PA.  Incidence of Acute Rheumatic Fever in New Zealand Children and Youth.  Journal of Paediatrics and Child Health. 2012; 48(8):685-91.
  3. Milne R, Lennon D, Stewart J, Vander Hoorn S, Scuffham PA.  Mortality and Hospitalisation Costs of Rheumatic Fever and Rheumatic Heart Disease in New Zealand.  Journal of Paediatrics and Child Health 2012;48(8):692-97 

Indigenous Health

  1. Le Grande M, Ski CF, Thompson D, Scuffham P, Kularatna S, Jackson AC, Brown A. Social and emotional wellbeing assessment instruments for use with Indigenous Australians: A critical review. Social Science & Medicine (early online https://doi.org/10.1016/j.socscimed.2017.06.046)
  2. Lalloo R, Kroon J, Tut O, Kularatna S, Jamieson LM, Wallace V, Boase R, Fernando S, Cadet-James Y, Scuffham PA, Johnson NW.       Effectiveness, cost-effectiveness and cost-benefit of a single annual professional intervention for the prevention of childhood dental caries in a remote rural Indigenous community. BMC Oral Health 2015; 15:99
  3. Nguyen K-H, Armfield N, Smith A, Scuffham PA. Cost-effectiveness analysis of a mobile ear screening and surveillance service versus an outreach screening, surveillance and surgical service for Indigenous children in Australia, PLoS One 2015; 10(9):1-16. e0138369.
  4. Elliott G, Smith AC, Bensink ME, Brown C, Stewart C, Perry C, Scuffham PA.  The Feasibility of a Community-Based Mobile Telehealth Screening Service for Aboriginal and Torres Strait Islander Children in Australia.  Telemedicine and e-Health 2010; 16(9): 950-6.

 Speciality Area: Health Economic Research

  1. Kularatna S, Byrnes J, Ski C, Stewart S, Chan Y-K, Carrington M, Scuffham PA. Comparison of the EQ-5D-3L and the SF-6D (SF-12) contemporaneous utility scores in patients with cardiovascular disease. Quality of Life Research (accepted 23 Jul 2017)
  2. Maru S, Byrnes J, Carrington MJ, Stewart S, Scuffham PA. Systematic review of trial-based analyses reporting the economic impact of heart failure management programs compared with usual care. European Journal of Cardiovascular Nursing 2016; 15(1):82-90
  3. Kularatna S, Byrnes J, Mervin MC, Scuffham PA. Health technology assessments reporting cost-effectiveness of transcatheter aortic valve implantation. International Journal of Technology Assessment in Health Care 2016; 32(3):89-96
  4. Maru S, Byrnes J, Carrington MJ, Stewart S, Scuffham PA. Economic Implications of Cardiovascular Disease Management Programs: Moving Beyond One-off Experiments. Expert Reviews of Pharmacoeconomics and Outcomes Research 2015; 15(4):657-666
  5. Maru S, Byrnes J, Whitty JA, Carrington MJ, Stewart S, Scuffham PA. Systematic review of model-based analyses reporting the cost-effectiveness and cost-utility of cardiovascular disease management programs. European Journal of Cardiovascular Nursing 2015; 14(1):26-33
  6. Iles R, Eley D, Hegney D, Patterson E, Young J, Del Mar C, Synnott R, Scuffham, PA. Revenue effects of Practice Nurse-led Care for chronic diseases. Australian Health Review 2014; 38:363-69
  7. Whitty JA, Stewart S, Carrington MJ, Calderone A, Marwick T, Horowitz JD, Krum H, Davidson PM, Macdonald PS, Reid C, Scuffham PA. Patient preferences and willingness-to-pay for a home or clinic based program of chronic heart failure management: findings from the Which? Trial. PloS One 2013; 8(3):e58347
  8. Ingles J, Yeates L, Hunt L, McGaughran J, Scuffham PA, Atherton J, Semsarian C. Health Status of Cardiac Genetic Disease Patients and their At-Risk Relatives.  International Journal of Cardiology. 2013;165(3):448-53.
  9. Marwick TH, Scuffham PA, Hunnick M.  Selection for Early Surgery in Asymptomatic Mitral Regurgitation:  A Markov Model.  International Journal of Cardiology. 2013;165(2):266-72.
  10. Gada H, Scuffham PA, Griffin B, Marwick TH.  Quality of Life Implications of Immediate Surgery and Watchful Waiting in Asymptomatic Aortic Stenosis - A decision-analytic model.  Circulation: Cardiovascular Quality and Outcomes 2011 Sep; 4(5):541-8.
  11. Priest VL, Scuffham PA, Hachamovitch R, Marwick TH.  Cost-Effectiveness of Coronary Computed Tomography and Cardiac Stress Imaging in the Emergency Department: A decision analytic model comparing diagnostic strategies for chest pain in patients at low risk of acute coronary syndromes.  JACC Cardiovascular Imaging 2011; 4(5), 549-56.
  12. Whitty JACarrington MJ, Stewart S, Holliday J, Marwick T, Scuffham PA.  Patient Preferences for the Delivery of Disease Management in Chronic Heart Failure: A qualitative study.  Journal of Cardiovascular Nursing 2012 May; 27(3), 201-7.