The Centre of Research Excellence (CRE) to Reduce Inequality in Heart Disease focuses on improving the heart health and outcomes of groups and communities i.e. Regional Australians, Indigenous Australians and International Health

Professor Simon Stewart

Professor Simon Stewart is the Inaugural Director of the Mary MacKillop Institute for Health Research

in Melbourne, Australia having stepped-down as Head of Preventative Cardiology at the world-renowned Baker IDI Heart and Diabetes Institute in 2014. As a National Health & Medical Research Council of Australia (NHMRC) Principal Research Fellow he is also the Director of the NHMRC Centre of Research Excellence (CRE) to Reduce Inequality in Heart Disease. 


Professor Stewart is a past recipient of the prestigious National Heart Foundation of

Australia’s Ralph Reader Overseas Fellowship and holds Fellowships with the European Society of Cardiology, the American Heart Association, and the Cardiac Society of Australia and New Zealand.


Consistent with the focus of the CRE to Reduce Inequality in Heart Disease, Professor Stewart’s research efforts have focused on: a) describing the evolving burden of cardiovascular disease in developed countries (e.g. Australia and the United Kingdom) and low-to-middle income countries (e.g. South Africa and Mozambique), b) determining who is most affected by this evolving burden and c) developing practical and affordable models of prevention and care in response.


Professor Stewart’s portfolio of health services research, therefore, encompasses whole population cohort studies to multicentre, randomised controlled trials of multidisciplinary interventions.


Professor Stewart is the Principal Investigator and Director of the CRE to Reduce Inequality of Heart Disease. In the first year of the CRE he will Chair the Executive Management Committee and will work closely with the other Investigators to meet the CRE’s aims and objectives, support the early-to-mid career researchers being funded via the CRE, and successfully undertake its planned portfolio of research.


Regional Australians

  1. Carrington MJ, Stewart S. Cardiovascular disease prevention via a nurse facilitated intervention clinic in a regional setting: The Protecting Healthy Hearts Program. Eur J Cardiovasc Nur. 2015; 14(4): 352-361.
  2. Krum H, Forbes A, Yallop J, Driscoll A, Croucher J, Chan B, Clark R, Davidson P, Huynh L, Kasper EK, Hunt D, Egan H, Stewart S, Piterman L, Tonkin A. Telephone Support to Rural and Remote Patients with Heart Failure: The Chronic Heart failure Assessment by Telephone (CHAT) study. Cardiovasc Ther. 2013; 31(4):230-7.
  3. Carrington MJ, Jennings GL, Clark RA, Stewart S. Assessing cardiovascular risk in regional areas: the healthy hearts -- beyond city limits program. BMC Health Serv Res. 2012;12(1):296.
  4. Clark RA, Coffee N, Turner D, Eckert K, van Gaans D, Wilkinson D, Stewart S, Tonkin A on behalf of the CARDIAC-ARIA Project Team. Application of geographic modeling techniques to quantify spatial access to health services before and after an acute cardiac event: The Cardiac ARIA project. Circulation, 2012;124(16):2006-14.
  5. Coffee N, Turner D, Clark RA, Eckert K, Coombe D, Bamford E, Hugo G, van Gaans D, Wilkinson D, Stewart S, Tonkin A on behalf of the CARDIAC-ARIA Project Team. Measuring national accessibility to cardiac services using geographic information systems. Applied Geography. 2012;34:445-55.

Indigenous Australians

  1. Brown A, Carrington MJ, McGrady M, Lee G, Zeitz C, Krum H, Rowley K, Stewart S. Cardiometabolic risk and disease in Indigenous Australians: The heart of the heart study. Int J Cardiol. Feb 2014; 171(3):377-83.
  2. Iyngkaran P, Harris M, Ilton M, Kangaharan N, Battersby M, Stewart S, Brown A. Implementing guideline based heart failure care in the Northern Territory: challenges and solutions. Heart Lung Circ. May 2014; 23(5):391-406. doi: 10.1016/j.hlc.2013.12.005.
  3. McGrady M, Krum H, Carrington MJ, Stewart S, Zeitz C, Lee GA, Marwick TH, Haluska BA, Brown AD. Heart failure, ventricular dysfunction and risk factor prevalence in Australian Aboriginal peoples: the Heart of the Heart Study. Heart. 2012;98(21):1562-7.
  4. Stewart S. Nurse-Led Care of Heart Failure: Will it Work in Remote Settings? Heart Lung Circ. 2012;21(10):644-7.
  5. Tuttle CSL, Carrington MJ, Stewart S, Brown A. Overcoming the tyranny of distance: An analysis of out-reach visits to optimize secondary prevention of cardiovascular disease in high risk individuals living in Central Australia. Aust J Rural Health. 2015. E-pub ahead of print. doi: 10.1111/ajr.12222

International Health

  1. Ogah OS, Sliwa K, Akinyemi JO, Falase AO, Stewart S. Hypertensive heart failure in Nigerian Africans: insights from the Abeokuta heart failure registry. Journal of Clinical Hypertension. 2015;17:263-72.
  2. Sliwa K, Carrington MJ, Becker A, Thienemann F, Ntsekhe M, Stewart S. Contribution of the human immunodeficiency virus/acquired immunodeficiency syndrome epidemic to de novo presentations of heart disease in the Heart of Soweto Study cohort. Euro Heart J 2012;33(7);866-74.
  3. Sliwa K, Lee GA, Carrington MJ, Obel P, Okreglicki A, Stewart S. Redefining the ECG in urban South Africans: Electrocardiographic findings in heart disease-free Africans. Int J Cardiol. 2012, E-Pub ahead of Print: 22795400.
  4. Sliwa K, Stewart S. Will a low-cost solar-powered blood pressure device turn the tide of the global cardiovascular disease epidemic? The Lancet 2011;378(9792):647-8.
  5. Stewart S, Carrington MJ, Pretorius S, Methusi P, Sliwa K. Standing at the crossroads between new and historically prevalent heart disease: Effects of migration and socio-economic factors in the Heart of Soweto cohort study. Euro Heart J 2011;32(4):492-9.

Chronic heart disease

  1. Stewart S, Ball J, Horowitz JD, Marwick TH, Mahadevan G, Wong C, Abhayaratna WP, Chan YK, Esterman A, Thompson DR, Scuffham PA, Carrington MJ. Standard versus atrial fibrillation-specific management strategy (SAFETY) to reduce recurrent admission and prolong survival: pragmatic, multicentre, randomized controlled trial. Lancet. 2015; 385(9970):775-784.
  2. Stewart S, Carrington MJ, Marwick TH, Davidson PM, Macdonald P, Horowitz JD, Krum H, Newton PJ, Reid C, Chan YK, Scuffham PA. Impact of Home Versus Clinic-Based Management of Chronic Heart Failure: The WHICH? (Which Heart Failure Intervention Is Most Cost-Effective & Consumer Friendly in Reducing Hospital Care) Multicenter, Randomized Trial. J Am Coll Cardiol. 2012;60(14):1239-48.
  3. Stewart S, Carrington MJ, Swemmer CH, Anderson C, Kurstjens NP, Amerena J, Brown A, Burrell LM, de Looze FJ, Harris M, Hung J, Krum H, Nelson M, Schlaich M, Stocks NP, Jennings GL. Effect of intensive structured care on individual blood pressure targets in primary care: multicentre randomised controlled trial. British Medical Journal. 2012;345, e7156.
  4. Carrington MJ, Ball J, Horowitz JD, Marwick TH, Mahadevan G, Wong C, Abhayaratna WP, Haluska B, Thompson DR, Scuffham PA, Stewart S. Navigating the fine line between benefit and risk in chronic atrial fibrillation: Rationale and design of the Standard versus Atrial Fibrillation spEcific managemenT studY (SAFETY). Int J Cardiol 2013; 166: 359-65.
  5. Chan YK, Stewart S, Calderone A, Scuffham PA, Goldstein S, Carrington MJ. Exploring the potential to remain "Young @ Heart": Initial findings of a multi-centre, randomised study of nurse-led, home-based intervention in a hybrid health care system. Int J Cardiol. 2012;154(1):52-8.